Treg Cell Therapy for Autoimmune Diseases

Regulatory T-cells (Tregs) expanded ex vivo from patient blood, modified for enhanced suppressive function, used in treating graft-versus-host disease post-transplant. HTS 3002.51.00.00 covers these as cell therapy products—biotechnologically modified cell cultures for immunotherapy. They restore immune tolerance by suppressing overactive responses.

Import Duty Rates by Country of Origin

Origin CountryMFN RateCh.99 SurchargesTotal Effective Rate
🇨🇳ChinaFreeFree
🇲🇽MexicoFreeFree
🇨🇦CanadaFreeFree
🇩🇪GermanyFreeFree
🇯🇵JapanFreeFree

Alternative Classifications

This product could be classified differently depending on its characteristics or intended use.

3002Same rate: Free

If classified as simple blood fractions without cell expansion

Unmodified blood extracts or antisera go under human blood products, not expanded/modified cell therapies.

3004.90Higher: 10% vs Free

If for finished medicinal preparations containing cell extracts

If mixed into medicaments or dosage forms, they become mixed therapeutic preparations in heading 3004.

Not sure which classification is right?

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Import Tips & Compliance

Include lot-specific potency assays and sterility test results in import documentation

Ship under IATA dangerous goods regulations for Category A infectious substances

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CAR-T Cell Therapy for Leukemia

Chimeric antigen receptor T-cell (CAR-T) therapy consists of patient-derived T-cells genetically modified to target CD19-positive cancer cells, used in treating relapsed B-cell acute lymphoblastic leukemia. Classified under HTS 3002.51.00.00 as cell therapy products, these are cell cultures modified via biotechnological processes for therapeutic use. They are administered intravenously after expansion and infusion preparation.

NK Cell Therapy for Solid Tumors

Natural killer (NK) cells from peripheral blood, cytokine-activated and expanded for adoptive transfer in treating melanoma and other solid tumors. As modified cell cultures for cancer immunotherapy, they classify under HTS 3002.51.00.00 cell therapy products. These cells directly lyse tumor targets without prior sensitization.

Mesenchymal Stem Cell Therapy for Osteoarthritis

Allogeneic mesenchymal stem cells (MSCs) derived from umbilical cord tissue, expanded and cryopreserved for intra-articular injection to reduce inflammation in knee osteoarthritis. Falls under HTS 3002.51.00.00 as cell therapy products due to their modified cell culture status for regenerative therapeutic purposes. These biologics promote cartilage repair via immunomodulatory effects.

iPSC-Derived Cardiomyocyte Therapy for Heart Failure

Induced pluripotent stem cell (iPSC)-derived cardiomyocytes for intramyocardial injection to repair damaged heart tissue post-myocardial infarction. These engineered cell cultures are cell therapy products under HTS 3002.51.00.00, modified biotechnologically for cardiac regeneration. They integrate and beat synchronously with host tissue.

Dendritic Cell Vaccine for Prostate Cancer

Autologous dendritic cells loaded with tumor-associated antigens (e.g., Provenge/sipuleucel-T), matured ex vivo for personalized cancer vaccination. HTS 3002.51.00.00 applies to these as cell therapy products—modified cell cultures for active immunotherapy. They prime T-cell responses against prostate cancer cells.