Human Plasma-Derived Immunoglobulin Fraction

IVIG (intravenous immunoglobulin) is a pooled human plasma fraction containing antibodies for immune deficiency treatment. Prepared via cold ethanol fractionation. While purified, retains blood fraction classification under HTS 3002.12.00.10.

Import Duty Rates by Country of Origin

Origin CountryMFN RateCh.99 SurchargesTotal Effective Rate
🇨🇳ChinaFree—Free
🇲🇽MexicoFree—Free
🇨🇦CanadaFree—Free
🇩🇪GermanyFree—Free
🇯🇵JapanFree—Free

Alternative Classifications

This product could be classified differently depending on its characteristics or intended use.

3002.90Higher: 10% vs Free

If classified as other immunological products like monoclonal antibodies

Highly specific peptides/proteins may fall under note 2 definition for 3002.90.

3004.39.00Same rate: Free

If when dispensed in retail pharmacy doses

Mixed or formulated for direct patient administration shifts to medicaments heading.

3504.00.10Higher: 22.5% vs Free

If isolated peptide fractions without immunological claim

Purified plasma proteins lose Chapter 30 status if not therapeutic/immunological.

Not sure which classification is right?

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Import Tips & Compliance

• Provide pool traceability from 10,000+ donors with NAT testing results for HIV/HBV/HCV

• Declare IgG content percentage and stabilization method (e.g

• 10% maltose)

• Avoid reclassification as finished medicament by maintaining 'blood fraction' documentation

Related Products under HTS 3002.12.00.10

Fresh Frozen Human Plasma

Fresh frozen human plasma is obtained from whole human blood and frozen within 8 hours of collection to preserve clotting factors. It is used therapeutically for patients with coagulopathies or massive transfusion needs. Classified under HTS 3002.12.00.10 as human blood plasma prepared for therapeutic uses.

Cryoprecipitated Antihemophilic Factor from Human Plasma

Cryoprecipitate is a human plasma fraction rich in factor VIII, fibrinogen, and von Willebrand factor, prepared by thawing frozen plasma at 1-6°C. It treats hemophilia A and fibrinogen deficiencies. Falls under HTS 3002.12.00.10 as a human blood fraction derived from plasma.

Human Plasma for Further Manufacture

Bulk human plasma supplied to fractionators for producing albumin, IVIG, and clotting factors. Prepared with therapeutic end-use in mind. Classified HTS 3002.12.00.10 as blood plasma for therapeutic applications.

Lyophilized Human Plasma for Surgical Use

Lyophilized (freeze-dried) human plasma is dehydrated plasma reconstituted with sterile water for volume replacement in surgery. It provides essential proteins and clotting factors. Classified in HTS 3002.12.00.10 as processed human blood plasma for therapeutic applications.

Pathogen-Reduced Human Plasma

Human plasma treated with amotosalen/UVA light to inactivate viruses, bacteria, and parasites while preserving therapeutic proteins. Used for transfusion in immunocompromised patients. HTS 3002.12.00.10 covers this modified human blood plasma.

Solvent/Detergent Treated Human Plasma

Human plasma treated with TNBP/Tween 80 to disrupt lipid envelopes of viruses, then purified. Used for transfusion medicine. Classifies as human blood fraction under HTS 3002.12.00.10 despite viral inactivation processing.