Synthetic Papaverine Hydrochloride from Canada
Synthetic papaverine hydrochloride replicates the opium-derived alkaloid structure through total chemical synthesis, used identically in pharmaceuticals. Covered under HTS 2939.19.10.00 as 'alkaloids, natural or reproduced by synthesis, and their salts' per heading language. This enables import of non-plant-extracted material meeting identical purity specs.
Duty Rate — Canada → United States
100%
Rate breakdown
9903.04.60100%Pharmaceuticals Annex IV: patented pharma articles — 100% floor rate
9903.05.860%Universal product exemption (U.S. note 52(b))
9903.05.900%Articles already subject to Section 232 (steel/aluminum/copper + derivatives, autos + parts, wood, medium/heavy vehicles + parts, semiconductors, patented pharma) — U.S. note 52(f)
Import Tips
• Include synthesis route documentation proving structural identity to natural papaverine; chiral purity confirmation essential
• Synthetic versions need identical impurity profile to natural; declare 'reproduced by synthesis' explicitly on commercial invoice
• Monitor for residual synthesis solvents (<500ppm); chapter note (e) permits transport solvents but not persistent impurities