Papaverine Hydrochloride USP
Papaverine hydrochloride is the salt form of papaverine, a benzylisoquinoline alkaloid derived from opium, used primarily as a smooth muscle relaxant in pharmaceutical applications. It falls under HTS 2939.19.10.00 as a salt of the opium alkaloid papaverine, consistent with chapter notes specifying alkaloids and their salts. This pure chemical compound is supplied as a white crystalline powder for compounding into injectables or oral medications.
Import Duty Rates by Country of Origin
| Origin Country | MFN Rate | Ch.99 Surcharges | Total Effective Rate |
|---|---|---|---|
| 🇨🇳China | Free | — | Free |
| 🇲🇽Mexico | Free | — | Free |
| 🇨🇦Canada | Free | — | Free |
| 🇩🇪Germany | Free | — | Free |
| 🇯🇵Japan | Free | — | Free |
Alternative Classifications
This product could be classified differently depending on its characteristics or intended use.
If chemically modified beyond simple salt formation
Derivatives other than salts, ethers, or esters of opium alkaloids fall under the 'other' alkaloid derivatives subheading per numerical order rule.
If pre-formulated into medicaments like injectables
Mixed or compounded with excipients for therapeutic use, these become medicaments of Chapter 30, excluding pure chemical compounds of Chapter 29.
If converted to sugar ethers or esters
Sugar derivatives of alkaloids are specifically directed to heading 2940 by chapter note (c), taking precedence over alkaloid classification.
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Import Tips & Compliance
• Verify USP or EP pharmacopeia grade certification and provide Certificate of Analysis (CoA) confirming purity >98% to avoid reclassification as impure mixtures
• Include FDA Drug Master File (DMF) references and ensure INN compliance for papaverine hydrochloride; declare as bulk API not finished dosage forms
Related Products under HTS 2939.19.10.00
Papaverine Hydrobromide Powder
Papaverine hydrobromide is a bromide salt of the opium alkaloid papaverine, utilized in pharmaceutical manufacturing for its antispasmodic properties. Classified under HTS 2939.19.10.00 as a salt of papaverine per the alkaloid heading structure. It is typically imported as a bulk fine chemical for further processing into vascular smooth muscle relaxants.
Synthetic Papaverine Hydrochloride
Synthetic papaverine hydrochloride replicates the opium-derived alkaloid structure through total chemical synthesis, used identically in pharmaceuticals. Covered under HTS 2939.19.10.00 as 'alkaloids, natural or reproduced by synthesis, and their salts' per heading language. This enables import of non-plant-extracted material meeting identical purity specs.
Papaverine Base Pure Powder
Papaverine base, the free alkaloid without salt formation, extracted from opium or synthesized, used in research and as intermediate for salt production. HTS 2939.19.10.00 includes the parent alkaloid 'papaverine and its salts' explicitly. Supplied as analytical reference standard or bulk chemical.
Papaverine Sulfate Pharmaceutical Grade
Papaverine sulfate, a sulfuric acid salt of the natural opium alkaloid papaverine, serves as a non-narcotic peripheral vasodilator in medical treatments. This product is explicitly covered by HTS 2939.19.10.00 for papaverine and its salts, as a separate chemically defined organic compound. It is imported as high-purity powder for hospital pharmacy compounding.