Nifedipine from Canada

Nifedipine is the prototype dihydropyridine calcium channel blocker used for angina and hypertension. This nitro-substituted aromatic heterocycle with nitrogen hetero-atoms classifies under HTS 2933.99.53.00. Bulk API imported under nitrogen atmosphere due to light sensitivity.

Duty Rate — Canada → United States

6.5%

Rate breakdown

9903.03.030%Articles the product of any country, as provided for in subdivision (aa)(ii) of U.S. note 2 to this subchapter

Import Tips

Amber glass or opaque HDPE only - light exposure converts to nitroso derivative

Polymorph I required for bioavailability - Form II dissolves slower

High potency Category 3 - dedicated equipment cleaning validation needed