Nifedipine from Canada
Nifedipine is the prototype dihydropyridine calcium channel blocker used for angina and hypertension. This nitro-substituted aromatic heterocycle with nitrogen hetero-atoms classifies under HTS 2933.99.53.00. Bulk API imported under nitrogen atmosphere due to light sensitivity.
Duty Rate — Canada → United States
100%
Rate breakdown
9903.04.6093.5%Pharmaceuticals: patented pharma articles — 100% floor rate
9903.05.900%Articles already subject to Section 232 (steel/aluminum/copper + derivatives, autos + parts, wood, medium/heavy vehicles + parts, semiconductors, patented pharma) — U.S. note 52(f)
Import Tips
• Amber glass or opaque HDPE only - light exposure converts to nitroso derivative
• Polymorph I required for bioavailability - Form II dissolves slower
• High potency Category 3 - dedicated equipment cleaning validation needed