Nifedipine

Nifedipine is the prototype dihydropyridine calcium channel blocker used for angina and hypertension. This nitro-substituted aromatic heterocycle with nitrogen hetero-atoms classifies under HTS 2933.99.53.00. Bulk API imported under nitrogen atmosphere due to light sensitivity.

Import Duty Rates by Country of Origin

Origin CountryMFN RateCh.99 SurchargesTotal Effective Rate
πŸ‡¨πŸ‡³China6.5%β€”6.5%
πŸ‡²πŸ‡½Mexico6.5%β€”6.5%
πŸ‡¨πŸ‡¦Canada6.5%β€”6.5%
πŸ‡©πŸ‡ͺGermany6.5%β€”6.5%
πŸ‡―πŸ‡΅Japan6.5%β€”6.5%

Alternative Classifications

This product could be classified differently depending on its characteristics or intended use.

2921.42.18.00Higher: 23.3% vs 6.5%

If amide function classification prevails

Different principal chemical function determines Chapter 29 subheading.

3004.90Higher: 10% vs 6.5%

If as sustained-release pellets

Any granulated or pelleted dosage form classifies as Chapter 30 product.

Not sure which classification is right?

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Import Tips & Compliance

β€’ Amber glass or opaque HDPE only - light exposure converts to nitroso derivative

β€’ Polymorph I required for bioavailability - Form II dissolves slower

β€’ High potency Category 3 - dedicated equipment cleaning validation needed

Related Products under HTS 2933.99.53.00

Diltiazem Hydrochloride

Diltiazem hydrochloride is a benzothiazepine derivative calcium channel antagonist used for hypertension, angina, and arrhythmias. Its nitrogen-containing heterocyclic structure qualifies it for HTS 2933.99.53.00 as an aromatic cardiovascular drug. Imported typically as bulk API powder for tablet manufacturing.

Felodipine

Felodipine is a vasoselective dihydropyridine calcium channel blocker for essential hypertension treatment. This aromatic nitrogen-heterocycle classifies under HTS 2933.99.53.00 as a cardiovascular drug in bulk form. Imported as free base or specific polymorphs for extended-release formulations.

Isradipine

Isradipine, a 1,4-dihydropyridine derivative, selectively blocks L-type calcium channels for hypertension therapy. Its nitrogen-heterocyclic aromatic structure fits HTS 2933.99.53.00 as a cardiovascular drug API. Typically imported as micronized powder for tablet coating.

Nimodipine

Nimodipine is a lipophilic 1,4-dihydropyridine indicated for cerebral vasospasm prevention post-subarachnoid hemorrhage. As a nitrogen-heterocyclic cardiovascular drug, it falls under HTS 2933.99.53.00. Imported as oily liquid or powder for IV and oral formulations.

Pravastatin Sodium

Pravastatin sodium, a hydrophilic HMG-CoA reductase inhibitor, lowers LDL cholesterol in cardiovascular disease prevention. Its complex nitrogen-heterocyclic structure qualifies under HTS 2933.99.53.00 as a cardiovascular drug. Sodium salt form imported as spray-dried amorphous powder.

Clopidogrel Bisulfate

Clopidogrel bisulfate, a thienopyridine P2Y12 inhibitor, prevents thrombotic events in cardiovascular patients. This aromatic nitrogen-heterocycle classifies under HTS 2933.99.53.00 as a cardiovascular antiplatelet drug. Form I crystalline powder imported for tablet manufacture.