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Nicardipine Hydrochloride

Nicardipine hydrochloride, a dihydropyridine calcium antagonist, treats acute hypertension and angina. As a nitrogen-heterocyclic aromatic compound, it qualifies under HTS 2933.99.53.00 for cardiovascular drug imports. Bulk API typically in crystalline powder form.

Import Duty Rates by Country of Origin

Origin Country	MFN Rate	Ch.99 Surcharges	Total Effective Rate
🇨🇳China	6.5%	—	6.5%
🇲🇽Mexico	6.5%	—	6.5%
🇨🇦Canada	6.5%	—	6.5%
🇩🇪Germany	6.5%	—	6.5%
🇯🇵Japan	6.5%	—	6.5%

Alternative Classifications

This product could be classified differently depending on its characteristics or intended use.

2933.52Higher: 10% vs 6.5%

If purine derivative structure predominates

Specific heterocyclic classes have dedicated provisions earlier in heading 2933.

3004.90Higher: 10% vs 6.5%

If imported in pre-filled syringes

Any finished dosage form, even sterile injectables, moves to Chapter 30 medicaments.

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Import Tips & Compliance

• Specify hydration state (anhydrous vs monohydrate) - affects solubility and classification stability

• Include chiral purity documentation (>99% S-enantiomer) for FDA ANDA submissions

Related Products under HTS 2933.99.53.00

Diltiazem Hydrochloride

Diltiazem hydrochloride is a benzothiazepine derivative calcium channel antagonist used for hypertension, angina, and arrhythmias. Its nitrogen-containing heterocyclic structure qualifies it for HTS 2933.99.53.00 as an aromatic cardiovascular drug. Imported typically as bulk API powder for tablet manufacturing.

Felodipine

Felodipine is a vasoselective dihydropyridine calcium channel blocker for essential hypertension treatment. This aromatic nitrogen-heterocycle classifies under HTS 2933.99.53.00 as a cardiovascular drug in bulk form. Imported as free base or specific polymorphs for extended-release formulations.

Isradipine

Isradipine, a 1,4-dihydropyridine derivative, selectively blocks L-type calcium channels for hypertension therapy. Its nitrogen-heterocyclic aromatic structure fits HTS 2933.99.53.00 as a cardiovascular drug API. Typically imported as micronized powder for tablet coating.

Nifedipine

Nifedipine is the prototype dihydropyridine calcium channel blocker used for angina and hypertension. This nitro-substituted aromatic heterocycle with nitrogen hetero-atoms classifies under HTS 2933.99.53.00. Bulk API imported under nitrogen atmosphere due to light sensitivity.

Nimodipine

Nimodipine is a lipophilic 1,4-dihydropyridine indicated for cerebral vasospasm prevention post-subarachnoid hemorrhage. As a nitrogen-heterocyclic cardiovascular drug, it falls under HTS 2933.99.53.00. Imported as oily liquid or powder for IV and oral formulations.

Pravastatin Sodium

Pravastatin sodium, a hydrophilic HMG-CoA reductase inhibitor, lowers LDL cholesterol in cardiovascular disease prevention. Its complex nitrogen-heterocyclic structure qualifies under HTS 2933.99.53.00 as a cardiovascular drug. Sodium salt form imported as spray-dried amorphous powder.