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2933.59.21.00/Promethazine Hydrochloride/Japan

Promethazine Hydrochloride from Japan

Promethazine hydrochloride is a first-generation antihistamine and phenothiazine derivative containing a modified aromatic pyrimidine-like structure, primarily used to treat motion sickness, nausea, and allergic reactions. It falls under HTS 2933.59.21.00 as an aromatic antihistamine principally used as an anti-nauseant, consistent with chapter notes for heterocyclic nitrogen compounds with pyrimidine rings. This chemically defined compound is imported in pure form for pharmaceutical formulation.

Duty Rate — Japan → United States

12.5%

Rate breakdown

9903.05.4912.5%Section 301 (forced labor) — Japan (col1 rate < 12.5 percent): MFN < 12.5% → total duty capped at 12.5%
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Import Tips

• Verify USP-grade purity and provide FDA Drug Master File; ensure COA confirms aromatic structure and antihistamine potency

• Common pitfall: mislabeling as general chemical vs drug triggers reclassification

• Obtain prior FDA import alert clearance for bulk APIs

Promethazine Hydrochloride from Japan — Import Duty Rate | HTS 2933.59.21.00