2933.59.21.00/Promethazine Hydrochloride/Canada

Promethazine Hydrochloride from Canada

Promethazine hydrochloride is a first-generation antihistamine and phenothiazine derivative containing a modified aromatic pyrimidine-like structure, primarily used to treat motion sickness, nausea, and allergic reactions. It falls under HTS 2933.59.21.00 as an aromatic antihistamine principally used as an anti-nauseant, consistent with chapter notes for heterocyclic nitrogen compounds with pyrimidine rings. This chemically defined compound is imported in pure form for pharmaceutical formulation.

Duty Rate — Canada → United States

100%

Rate breakdown

9903.04.6093.5%Except as provided in heading 9903.04.61, patented pharmaceutical articles as provided for in subdivisions (c) and (d) of U.S. note 40 to this subchapter

9903.05.900%Articles of aluminum, of steel or of copper or derivative aluminum or steel articles; passenger vehicles (sedans, sport utility vehicles, crossover utility vehicles, minivans and cargo vans) and light trucks; parts of passenger vehicles (sedans, sport utility vehicles, crossover utility vehicles, minivans and cargo vans) and light trucks; medium- and heavy-duty vehicles; parts of medium- and heavy-duty vehicles; wood products; patented pharmaceutical articles; and semiconductor articles, as provided in subdivision (f) of U.S. note 52 to this subchapter

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Import Tips

• Verify USP-grade purity and provide FDA Drug Master File; ensure COA confirms aromatic structure and antihistamine potency

• Common pitfall: mislabeling as general chemical vs drug triggers reclassification

• Obtain prior FDA import alert clearance for bulk APIs