Econazole Nitrate USP
Econazole nitrate, a broad-spectrum imidazole antifungal drug, falls under HTS 2933.29.4500 due to its characteristic unfused imidazole ring structure. Used primarily in dermatological treatments for fungal infections of skin and nails.
Import Duty Rates by Country of Origin
| Origin Country | MFN Rate | Ch.99 Surcharges | Total Effective Rate |
|---|---|---|---|
| π¨π³China | 3.7% | +25.0% | 28.7% |
| π²π½Mexico | 3.7% | β | 3.7% |
| π¨π¦Canada | 3.7% | β | 3.7% |
| π©πͺGermany | 3.7% | β | 3.7% |
| π―π΅Japan | 3.7% | β | 3.7% |
Alternative Classifications
This product could be classified differently depending on its characteristics or intended use.
If as finished dosage form
Oral or topical medicaments containing econazole shift to Chapter 30 classification.
If primary carboxamide function dominates
Classification follows principal function per Chapter Note 3; carboxamide may take precedence over imidazole.
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Import Tips & Compliance
β’ Provide polymorphic form characterization; nitrate salts prone to FDA scrutiny on crystal form stability
β’ Include forced degradation studies in submission; common detention cause is insufficient stability data
β’ Ensure proper nitrate content assay; over 0.1% impurities triggers import alert
Related Products under HTS 2933.29.45.00
Metronidazole USP
Metronidazole is a synthetic nitroimidazole derivative classified as a drug under HTS 2933.29.4500 due to its unfused imidazole ring structure and primary use as an antibiotic. It treats anaerobic bacterial infections, protozoal infections like trichomoniasis, and certain gastrointestinal conditions.
Clotrimazole API
Clotrimazole is an imidazole antifungal agent used in pharmaceutical formulations under HTS 2933.29.4500 for its unfused imidazole ring. It inhibits ergosterol synthesis in fungal cell membranes, treating conditions like athlete's foot and yeast infections.
Miconazole Nitrate BP
Miconazole nitrate, an imidazole-class antifungal drug under HTS 2933.29.4500, features an unfused imidazole ring essential for its ergosterol biosynthesis inhibition. Widely used in oral, topical, and vaginal antifungal treatments.
Ketoconazole USP
Ketoconazole, a synthetic imidazole antifungal drug classified under HTS 2933.29.4500, contains an unfused imidazole ring critical to its mechanism. Used systemically for serious fungal infections and topically for dandruff/seborrheic dermatitis.
Tioconazole API
Tioconazole, a 1-substituted imidazole antifungal under HTS 2933.29.4500, targets vaginal candidiasis through ergosterol binding. Its unfused imidazole ring defines its Chapter 29 chemical classification as a pharmaceutical drug substance.
Omoconazole Pharmaceutical Reference Standard
Omoconazole, a development-stage imidazole antifungal drug substance under HTS 2933.29.4500, features the unfused imidazole ring characteristic of this tariff provision. Used in clinical trials and analytical reference standards.