Clotrimazole API
Clotrimazole is an imidazole antifungal agent used in pharmaceutical formulations under HTS 2933.29.4500 for its unfused imidazole ring. It inhibits ergosterol synthesis in fungal cell membranes, treating conditions like athlete's foot and yeast infections.
Import Duty Rates by Country of Origin
Alternative Classifications
This product could be classified differently depending on its characteristics or intended use.
If marketed as pesticide or disinfectant
Imidazole compounds used for non-pharmaceutical disinfection fall under Chapter 38 pesticides.
If for research chemical grade not USP
Non-pharmaceutical grade or lab reagent imidazole derivatives classified as 'other' chemicals.
If in topical cream or ointment form
Finished topical medicaments containing clotrimazole classified by dosage form in Chapter 30.
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Import Tips & Compliance
• Include GMP certificate from manufacturing site; FDA frequently detains antifungal APIs without it
• Document impurity profiles per ICH guidelines; residual solvents testing often overlooked
• Label clearly as bulk pharmaceutical chemical to prevent classification as consumer product
Related Products under HTS 2933.29.45.00
Metronidazole USP
Metronidazole is a synthetic nitroimidazole derivative classified as a drug under HTS 2933.29.4500 due to its unfused imidazole ring structure and primary use as an antibiotic. It treats anaerobic bacterial infections, protozoal infections like trichomoniasis, and certain gastrointestinal conditions.
Econazole Nitrate USP
Econazole nitrate, a broad-spectrum imidazole antifungal drug, falls under HTS 2933.29.4500 due to its characteristic unfused imidazole ring structure. Used primarily in dermatological treatments for fungal infections of skin and nails.
Miconazole Nitrate BP
Miconazole nitrate, an imidazole-class antifungal drug under HTS 2933.29.4500, features an unfused imidazole ring essential for its ergosterol biosynthesis inhibition. Widely used in oral, topical, and vaginal antifungal treatments.
Ketoconazole USP
Ketoconazole, a synthetic imidazole antifungal drug classified under HTS 2933.29.4500, contains an unfused imidazole ring critical to its mechanism. Used systemically for serious fungal infections and topically for dandruff/seborrheic dermatitis.
Tioconazole API
Tioconazole, a 1-substituted imidazole antifungal under HTS 2933.29.4500, targets vaginal candidiasis through ergosterol binding. Its unfused imidazole ring defines its Chapter 29 chemical classification as a pharmaceutical drug substance.
Omoconazole Pharmaceutical Reference Standard
Omoconazole, a development-stage imidazole antifungal drug substance under HTS 2933.29.4500, features the unfused imidazole ring characteristic of this tariff provision. Used in clinical trials and analytical reference standards.