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Penicillin G Amidase Enzyme Powder from Japan

Penicillin G amidase is a purified enzyme used in the biopharmaceutical industry to hydrolyze penicillin G into 6-aminopenicillanic acid (6-APA), a key intermediate for semi-synthetic antibiotics. This powder form is specifically classified under HTS 3507.90.20.00 as it matches the description of Penicillin G amidase, a prepared enzyme not elsewhere specified.

Duty Rate — Japan → United States

12.5%

Rate breakdown

9903.05.4912.5%Section 301 (forced labor) — Japan (col1 rate < 12.5 percent): MFN < 12.5% → total duty capped at 12.5%

Import Tips

Obtain a detailed Certificate of Analysis (CoA) verifying the enzyme's activity and purity to satisfy FDA and CBP requirements for biotech imports

Declare as 'Penicillin G Amidase' explicitly on commercial invoices to avoid misclassification into general enzyme categories

Ensure cold chain documentation for refrigerated shipments, as improper storage can degrade enzyme activity and lead to customs holds