Ephedrine Hydrochloride
Ephedrine hydrochloride is the hydrochloride salt of ephedrine, a natural alkaloid derived from Ephedra plants, reproduced by synthesis for pharmaceutical use. It falls under HTS 2939.49.0300 as a derivative salt of ephedra alkaloids, used primarily in bronchodilators and nasal decongestants. This classification covers synthetic reproductions meeting chapter 29 criteria for separate chemically defined organic compounds.
Import Duty Rates by Country of Origin
| Origin Country | MFN Rate | Ch.99 Surcharges | Total Effective Rate |
|---|---|---|---|
| 🇨🇳China | Free | +100.0% | 100% |
| 🇲🇽Mexico | Free | +100.0% | 100% |
| 🇨🇦Canada | Free | +100.0% | 100% |
| 🇩🇪Germany | Free | +15.0% | 15% |
| 🇯🇵Japan | Free | +15.0% | 15% |
Alternative Classifications
This product could be classified differently depending on its characteristics or intended use.
If formulated into finished dosage forms like tablets or syrups
Medicinal preparations containing ephedrine salts are classified in Chapter 30 based on therapeutic use rather than chemical composition.
If containing thebaine as principal alkaloid instead of ephedrine
Chapter note requires classification in the last occurring heading; thebaine-specific subheading takes precedence over 'other' ephedra derivatives.
If imported as mixtures with >2% impurities or multiple alkaloids
Mixtures not meeting 'separate chemically defined compound' criteria in chapter note (a) fall under prepared chemical mixtures.
Not sure which classification is right?
The Tariff Assistant works through the GRI rules on your specific product to reach the right HTS code — and can price the duty on it in the same conversation.
Import Tips & Compliance
• Obtain DEA registration and import permit as it's a List I chemical under US controlled substances regulations
• Provide certificate of analysis confirming purity >98% and synthetic origin to avoid natural product misclassification
• Ensure proper labeling as 'pharmaceutical intermediate' to prevent reclassification under Chapter 30 drug preparations
Related Products under HTS 2939.49.03.00
Pseudoephedrine Hydrochloride USP
Pseudoephedrine hydrochloride is the USP-grade salt of pseudoephedrine, an ephedra alkaloid stereoisomer synthesized for OTC cold medications. Classified under HTS 2939.49.0300 as an ephedra alkaloid derivative salt per chapter notes allowing synthetic reproductions. Used as a nasal decongestant in products like Sudafed.
Ephedrine Sulfate Powder
Ephedrine sulfate is the sulfuric acid salt of ephedrine alkaloid, synthesized for injectable pharmaceutical applications and asthma treatment. It qualifies under HTS 2939.49.0300 as an ephedra alkaloid salt per chapter classification rules for organic salts. The pure chemical form distinguishes it from formulated drugs.
Phenylpropanolamine Hydrochloride
Phenylpropanolamine HCl is a synthetic ephedrine derivative salt used historically as an appetite suppressant and decongestant. Falls under HTS 2939.49.0300 as an 'other' ephedra alkaloid derivative per the heading's scope for synthetic reproductions. Now restricted but still imported for specific pharmaceutical uses.
Methylephedrine
Methylephedrine is an N-methylated ether derivative of ephedrine, synthesized as a bronchodilator in some Asian markets. Classified in HTS 2939.49.0300 covering ethers and other derivatives of ephedra alkaloids. The modification maintains its classification within the specific ephedra subheading.