Dexamethasone
Dexamethasone is a synthetic fluorinated glucocorticoid, a halogenated derivative of cortisol (an adrenal cortical hormone), used primarily for its potent anti-inflammatory and immunosuppressive effects. It falls under HTS 2937.22.00.00 as a halogenated derivative of adrenal cortical hormones per Chapter 29 notes defining such compounds by their chemical structure and hormonal function.
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Alternative Classifications
This product could be classified differently depending on its characteristics or intended use.
If unhalogenated steroid hormone analog
Lacks halogen substitution on the steroid nucleus, classifying as other steroidal hormones under later numerical heading per Chapter 29 note.
If formulated as finished dosage form (tablets, injections)
Bulk API becomes medicaments when mixed with excipients for therapeutic use, moving from Chapter 29 chemicals to Chapter 30 pharmaceuticals.
If for veterinary use only, not primarily hormonal
End-use determination shifts classification if not meeting 'used primarily as hormones' criterion in heading 2937 note.
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Import Tips & Compliance
• Obtain FDA approval and Drug Master File (DMF) prior to import; ensure certificate of analysis confirms purity >99% and halogen content
• Provide detailed chemical specifications and CAS number (50-02-2) on commercial invoice to avoid misclassification as general steroids
• Verify compliance with USP/EP monographs; common pitfall is inadequate stability data for transport conditions
Related Products under HTS 2937.22.00.00
Triamcinolone Acetonide
Triamcinolone acetonide is a fluorinated derivative of adrenal cortical hormones (9α-fluoro-16α-hydroxyprednisolone acetonide) used primarily for its glucocorticoid hormonal activity in treating inflammation. Falls under HTS 2937.22.00.00 as a separate chemically defined halogenated steroidal hormone per Chapter 29 scope.
Clobetasol Propionate
Clobetasol propionate is a highly potent chlorinated and fluorinated derivative of prednisolone (adrenal cortical hormone origin) used topically as a super-potent glucocorticoid. Meets HTS 2937.22.00.00 criteria as a halogenated (Cl/F) steroidal hormone per Chapter 29 chemical definitions.
Fluorometholone
Fluorometholone is a 6α-methyl-9α-fluoro prednisolone derivative, halogenated adrenal cortical hormone analog used primarily in ophthalmic suspensions for anti-inflammatory effects. Classified under HTS 2937.22.00.00 as chemically defined halogenated steroidal hormone.
Desonide
Desonide is a fluorinated, low-potency corticosteroid (11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 17-butyrate 21-acetate) derived from adrenal cortical hormones. Qualifies for HTS 2937.22.00.00 as halogenated derivative used primarily for topical hormonal therapy.
Mometasone Furoate
Mometasone furoate is a potent 21-chloro-11β,17-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17-(2-furoate) halogenated corticosteroid from adrenal cortical hormone series. HTS 2937.22.00.00 applies due to chlorine halogenation and primary hormonal use.
Betamethasone
Betamethasone is a potent fluorinated corticosteroid derived from adrenal cortical hormones, featuring fluorine halogenation at key positions for enhanced glucocorticoid activity. Classified under HTS 2937.22.00.00 as it meets Chapter 29 criteria for chemically defined halogenated steroidal hormones used primarily for anti-inflammatory hormonal effects.