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Thiamine Pyrophosphate (TPP) Cofactor

Thiamine pyrophosphate is the biologically active coenzyme form of vitamin B1, essential for carbohydrate metabolism. It qualifies under HTS 2936.22.00.00 as a thiamine derivative used primarily as a vitamin in biochemical research and therapeutics. Primarily supplied as lyophilized powder for IV formulations.

Import Duty Rates by Country of Origin

Origin CountryMFN RateCh.99 SurchargesTotal Effective Rate
🇨🇳ChinaFree+100.0%100%
🇲🇽MexicoFree+100.0%100%
🇨🇦CanadaFree+100.0%100%
🇩🇪GermanyFree+15.0%15%
🇯🇵JapanFree+15.0%15%

Alternative Classifications

This product could be classified differently depending on its characteristics or intended use.

3002.90Lower: 12.5% vs 100%

If in human blood plasma substitutes or immunological products

TPP in biological therapeutics falls under Chapter 30 per chapter exclusion notes.

3822Lower: 12.5% vs 100%

If as certified reference standard for lab diagnostics

Laboratory reagent-grade TPP classifies as diagnostic reagents under Chapter 38.

2934.99.15.00Higher: 112.5% vs 100%

If containing nucleic acid modifications

Nucleotide-linked thiamine derivatives move to heterocyclic compounds heading.

Not sure which classification is right?

The Tariff Assistant works through the GRI rules on your specific product to reach the right HTS code — and can price the duty on it in the same conversation.

Import Tips & Compliance

• Include biotech end-use statement if for research to avoid pharmaceutical scrutiny

• Cold chain documentation required for lyophilized forms to maintain >95% activity

• Declare CAS number 154-87-0 on entry to facilitate chemical identification

Related Products under HTS 2936.22.00.00

Thiamine Hydrochloride USP

Thiamine hydrochloride is the most common salt form of vitamin B1, a water-soluble derivative used primarily as a vitamin supplement. It falls under HTS 2936.22.00.00 as a chemically defined derivative of thiamine employed in pharmaceutical and nutritional applications. This synthetic form ensures stability for tablets, injections, and fortified foods.

Thiamine Mononitrate Powder

Thiamine mononitrate is a stable, non-hygroscopic derivative of vitamin B1 widely used in food fortification and multivitamin supplements. Classified under HTS 2936.22.00.00 as a synthetic vitamin B1 derivative for nutritional purposes. Its superior stability makes it ideal for flour enrichment and dry premixes.

Benfotiamine Pharmaceutical Grade

Benfotiamine is a lipid-soluble thiamine derivative with enhanced bioavailability, used in neuropathy treatments. Falls under HTS 2936.22.00.00 as a synthetic vitamin B1 derivative for pharmaceutical applications. Its S-benzoyl structure improves absorption over standard thiamine forms.

Thiamine Tetrahydrofurfuryl Disulfide (TTFD)

TTFD is an allithiamine-type derivative of vitamin B1 with superior transdermal absorption properties. Classified under HTS 2936.22.00.00 as it functions primarily as a vitamin derivative in nutritional supplements. Popular in Japan for energy and cognitive support formulations.

Fursultiamine Hydrochloride

Fursultiamine hydrochloride is a disulfide derivative of thiamine with prolonged action, used in B1 deficiency treatments. It meets HTS 2936.22.00.00 criteria as a derivative used primarily as a vitamin in injectable and oral pharmaceuticals. Converts to active thiamine in vivo.

Thiamine Allyl Disulfide

Thiamine allyl disulfide (TAD) is a lipophilic B1 derivative naturally found in garlic, used in nutritional supplements. Classified under HTS 2936.22.00.00 for its primary vitamin function despite organo-sulfur structure. Provides garlic-like bioavailability enhancement.