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6R-trans-7-Amino-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid from Japan

This beta-lactam nucleus (6R-trans-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid) is explicitly listed in HTS 2934.99.70.00 as a heterocyclic intermediate for cephalosporin antibiotic synthesis. The bicyclic ring system with sulfur and nitrogen heteroatoms qualifies it as an 'other heterocyclic compound' under heading 2934.

Duty Rate — Japan → United States

12.5%

Rate breakdown

9903.05.4912.5%Section 301 (forced labor) — Japan (col1 rate < 12.5 percent): MFN < 12.5% → total duty capped at 12.5%

Import Tips

FDA import alert 99-20 may apply; provide DMF or drug master file for pharmaceutical intermediates

Include stereochemical confirmation (6R-trans configuration) via chiral HPLC analysis

Classify as UN 2811 (toxic solid, organic) with appropriate GHS labeling