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Methotrexate from Canada

Methotrexate is a folic acid antagonist featuring pteridine heterocyclic rings, used as an antineoplastic and immunosuppressant drug. It qualifies for HTS 2934.99.30.00 as an aromatic heterocyclic drug compound used in rheumatoid arthritis and cancer treatments.

Duty Rate — Canada → United States

16.5%

Rate breakdown

9903.05.2910%Section 301 (forced labor) — additional 10% ad valorem on products of Canada

Import Tips

Submit Type II Drug Master Files and bioequivalence data for generic API approval during import clearance

Provide impurity profiles and chiral purity certificates since it's a single enantiomer drug substance

Include cytotoxic hazard labeling and UN shipping declarations for safe transport compliance