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3-Methylene-7-(2-Phenoxyacetamido)-Cephan-4-Carboxylic Acid, p-Nitrobenzyl Ester, 1-Oxide from Japan

This complex beta-lactam derivative is a specific cephalosporin intermediate with a dihydrothiazine ring, explicitly named in HTS 2934.99.03.00 as an aromatic/modified aromatic heterocyclic compound. The p-nitrobenzyl ester protects the carboxylic acid during synthesis of semi-synthetic antibiotics. It qualifies under Chapter 29 for chemically defined heterocyclic compounds used in pharmaceutical manufacturing.

Duty Rate — Japan → United States

27.5%

Rate breakdown

9903.04.6215%Patented pharmaceutical articles that are the product of Japan, of a European Union member country, of South Korea, of Switzerland, or of Liechtenstein as provided for in subdivisions (c) and (f) of U.S. note 40 to this subchapter
9903.05.4912.5%Except for products described in headings 9903.05.85–9903.05.92, articles the product of Japan, with an ad valorem (or ad valorem equivalent) rate of duty under column 1 less than 12.5 percent, as provided for in U.S. note 52 to this subchapter

Import Tips

• Submit HPLC chromatograms and structural confirmation to verify exact cephalosporin intermediate matching the HTS description

• Include DEA precursor documentation if applicable, as beta-lactam derivatives may trigger controlled substance scrutiny

• Ensure cold chain documentation (2-8°C) as instability affects classification validity under Chapter 29 solvent notes