Ivabradine Hydrochloride from China
Ivabradine hydrochloride selectively inhibits funny current (If) in sinoatrial node for heart rate reduction in chronic heart failure. Nitrogen-heterocyclic aromatic compound under HTS 2933.99.53.00. Bulk API as crystalline HCl salt.
Duty Rate — China → United States
19%
Rate breakdown
9903.05.3112.5%Section 301 (forced labor) — additional 12.5% ad valorem on products of China
Import Tips
• Phosphenes (visual effects) class effect - include ophthalmology data
• CYP3A4 substrate - extensive DDI studies required
• Highly potent - 5-7.5mg doses require content uniformity focus