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Isradipine from Japan

Isradipine, a 1,4-dihydropyridine derivative, selectively blocks L-type calcium channels for hypertension therapy. Its nitrogen-heterocyclic aromatic structure fits HTS 2933.99.53.00 as a cardiovascular drug API. Typically imported as micronized powder for tablet coating.

Duty Rate — Japan → United States

12.5%

Rate breakdown

9903.05.4912.5%Section 301 (forced labor) — Japan (col1 rate < 12.5 percent): MFN < 12.5% → total duty capped at 12.5%

Import Tips

D50 particle size 5-15μm critical - include laser diffraction report

Photostability testing required due to yellowing tendency

Single-source API often - verify supplier DMF status with FDA