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Cyclizine Hydrochloride from Japan

Cyclizine hydrochloride is a piperazine-based antihistamine used mainly for preventing motion sickness and treating vertigo/nausea. Its heterocyclic structure with piperazine ring qualifies it under HTS 2933.59.21.00 as an aromatic antihistamine anti-nauseant. Chapter notes confirm classification for separate chemically defined compounds with nitrogen hetero-atoms.

Duty Rate — Japan → United States

15%

Rate breakdown

9903.04.628.5%Patented pharmaceutical articles that are the product of Japan, of a European Union member country, of South Korea, of Switzerland, or of Liechtenstein as provided for in subdivisions (c) and (f) of U.S. note 40 to this subchapter
9903.05.900%Articles of aluminum, of steel or of copper or derivative aluminum or steel articles; passenger vehicles (sedans, sport utility vehicles, crossover utility vehicles, minivans and cargo vans) and light trucks; parts of passenger vehicles (sedans, sport utility vehicles, crossover utility vehicles, minivans and cargo vans) and light trucks; medium- and heavy-duty vehicles; parts of medium- and heavy-duty vehicles; wood products; patented pharmaceutical articles; and semiconductor articles, as provided in subdivision (f) of U.S. note 52 to this subchapter

Import Tips

• Include stability data for hydrochloride salt per chapter note (f); avoid anti-dusting agents that imply specific use

• Pitfall: bulk vs diluted forms—ensure solvent use only for transport/safety

• FDA prior notice mandatory for APIs