Methyl Nicotinate

Methyl nicotinate, a pyridine-3-carboxylate methyl ester, is used in topical rubefacients and veterinary pharmaceuticals for its counterirritant properties. This unfused pyridine ring compound is covered by HTS 2933.39.61 via additional U.S. note 3 to section VI. Bulk imported for transdermal applications.

Import Duty Rates by Country of Origin

Origin CountryMFN RateCh.99 SurchargesTotal Effective Rate
🇨🇳China6.5%6.5%
🇲🇽Mexico6.5%6.5%
🇨🇦Canada6.5%6.5%
🇩🇪Germany6.5%6.5%
🇯🇵Japan6.5%6.5%

Alternative Classifications

This product could be classified differently depending on its characteristics or intended use.

2916.31.20.00Higher: 41.5% vs 6.5%

If for bulk benzoic acid esters without pyridine emphasis

Chapter notes prioritize ester classification with acid-function compounds unless heterocyclic structure dominates.

3003.90.01Lower: Free vs 6.5%

If in bulk medicinal formulations

Medicaments in bulk (not retail packed) shift to Chapter 30.

3824.99Higher: 15% vs 6.5%

If mixture exceeds 95% purity threshold

Impure chemical mixtures may fall under heading 3824 for prepared chemical products.

Not sure which classification is right?

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Import Tips & Compliance

Submit veterinary drug master files if destined for animal health products to preempt APHIS review

Test for residual solvents per ICH guidelines; include results in import documentation

Segregate from food-contact shipments to prevent cross-contamination flags

Related Products under HTS 2933.39.61

Nicotine Bitartrate Dihydrate

Nicotine bitartrate dihydrate is a heterocyclic compound containing an unfused pyridine ring, used primarily in pharmaceutical formulations for smoking cessation aids like nicotine gums and patches. It falls under HTS 2933.39.61 as a pyridine derivative specified in additional U.S. note 3 to section VI, which covers certain regulated organic chemicals. This salt form ensures stability for medical applications.

Pyridine-3-Carboxylic Acid (Niacin)

Pyridine-3-carboxylic acid, commonly known as niacin or vitamin B3, is a chemically defined compound with an unfused pyridine ring used in nutritional supplements and pharmaceuticals. Classified under HTS 2933.39.61 per additional U.S. note 3 to section VI for specific pyridine derivatives. It's imported as a bulk API for fortification of foods and multivitamins.

Ethyl Nicotinate

Ethyl nicotinate is the ethyl ester of nicotinic acid, featuring an unfused pyridine ring, used topically in pharmaceuticals for peripheral vasodilator effects and in cosmetics. It qualifies for HTS 2933.39.61 under additional U.S. note 3 to section VI as a specified pyridine derivative. Commonly imported for compounding in creams and gels.

Isonicotinic Acid Hydrazide (INH)

Isonicotinic acid hydrazide (INH), or isoniazid, contains an unfused pyridine ring and serves as a first-line antituberculosis drug API. Classified in HTS 2933.39.61 per additional U.S. note 3 to section VI for specified pyridine compounds. Essential for generic TB treatment manufacturing.

Pyridine-4-Carboxylic Acid

Pyridine-4-carboxylic acid (isonicotinic acid) is a key intermediate with an unfused pyridine ring used in synthesizing pharmaceuticals like isoniazid. It falls under HTS 2933.39.61 as specified in additional U.S. note 3 to section VI. Primarily imported for fine chemical synthesis.

2-Aminopyridine

2-Aminopyridine is a simple unfused pyridine ring compound with an amino group, used as a chemical intermediate in agrochemicals and pharmaceuticals. Covered by HTS 2933.39.61 through additional U.S. note 3 to section VI for regulated pyridines. High-purity grades for synthesis.