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Sertraline Hydrochloride

Sertraline HCl (Zoloft API) is an SSRI antidepressant containing a tetrahydroisoquinoline structure with nitrogen heteroatoms. It falls under HTS 2933.39.31.00 as a psychotherapeutic agent with unfused pyridine-related ring systems.

Import Duty Rates by Country of Origin

Origin CountryMFN RateCh.99 SurchargesTotal Effective Rate
🇨🇳China6.5%+106.0%112.5%
🇲🇽Mexico6.5%+103.5%110%
🇨🇦Canada6.5%+103.5%110%
🇩🇪GermanyFree+18.5%18.5%
🇯🇵JapanFree+21.0%21%

Alternative Classifications

This product could be classified differently depending on its characteristics or intended use.

2933.49Lower: 19% vs 112.5%

If the compound lacks the specific pyridine ring structure

Other heterocyclic compounds with nitrogen go to different 2933.49 subheadings

3004.90Lower: 12.5% vs 112.5%

If imported in measured doses or packaged medicaments

Finished antidepressant formulations classified in Chapter 30

2922.19Lower: 19% vs 112.5%

If oxygen function dominates over heterocyclic classification

Amino acid derivatives with oxygen functions classified by oxygen function first

Not sure which classification is right?

The Tariff Assistant works through the GRI rules on your specific product to reach the right HTS code — and can price the duty on it in the same conversation.

Import Tips & Compliance

• Submit FDA Drug Master File and ensure API meets cGMP manufacturing standards

• Include stability data and retest date on Certificate of Analysis

• Avoid common pitfall of misclassifying as dosage form instead of bulk API

Related Products under HTS 2933.39.31.00

Fluoxetine Hydrochloride

Fluoxetine hydrochloride is the active pharmaceutical ingredient in Prozac, a selective serotonin reuptake inhibitor (SSRI) used primarily as an antidepressant. It contains an unfused pyridine ring in its heterocyclic structure, qualifying it for classification under HTS 2933.39.31.00 as a psychotherapeutic agent.

Paroxetine Hydrochloride

Paroxetine HCl, the API in Paxil, is an SSRI antidepressant featuring a piperidine ring (hydrogenated pyridine) in its structure. Classified under HTS 2933.39.31.00 due to its psychotherapeutic antidepressant function and nitrogen heterocyclic composition.

Escitalopram Oxalate

Escitalopram oxalate, the active ingredient in Lexapro, is the S-enantiomer of citalopram and functions as an SSRI antidepressant. Its diaminobenzofuran structure with piperidine ring places it under HTS 2933.39.31.00 for psychotherapeutic agents.

Venlafaxine Hydrochloride

Venlafaxine HCl (Effexor API) is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant with a phenethylamine structure containing nitrogen heterocycles. Classified in HTS 2933.39.31.00 as a psychotherapeutic antidepressant agent.

Duloxetine Hydrochloride

Duloxetine HCl (Cymbalta API), an SNRI antidepressant, features a naphthalene structure with piperazine heterocyclic ring. Falls under HTS 2933.39.31.00 due to its psychotherapeutic classification and nitrogen heteroatom content.

Buspirone Hydrochloride

Buspirone HCl is an anxiolytic tranquilizer (not benzodiazepine) used for generalized anxiety disorder, containing azaspirodecanedione with piperazine and pyridine-like structures. Classified under HTS 2933.39.31.00 as a psychotherapeutic tranquilizer.