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Captopril from Japan

Captopril, (2S)-1-[(2S)-3-mercapto-2-methylpropionyl]-L-proline, contains a mercaptocarboxylic acid side chain. Despite complex structure, classified under HTS 2930.90.4920 as its mercapto acid functionality defines the organo-sulfur nature per Chapter 29. Pharmaceutical API for hypertension treatment.

Duty Rate — Japan → United States

23.3%

Rate breakdown

9903.04.6210.8%Patented pharmaceutical articles that are the product of Japan, of a European Union member country, of South Korea, of Switzerland, or of Liechtenstein as provided for in subdivisions (c) and (f) of U.S. note 40 to this subchapter
9903.05.4912.5%Except for products described in headings 9903.05.85–9903.05.92, articles the product of Japan, with an ad valorem (or ad valorem equivalent) rate of duty under column 1 less than 12.5 percent, as provided for in U.S. note 52 to this subchapter

Import Tips

• FDA DMF and USP certificate mandatory; verify chiral purity >99.5% ee

• Controlled substance precursor monitoring; DEA import permit may apply

• Classify bulk API only; tablets move to Chapter 30 pharmaceuticals