4-Cyano-2-dimethylamino-4,4-diphenylbutane from China

This is a specific nitrile-function organic compound used primarily as an intermediate in the synthesis of methadone (INN), a pharmaceutical opioid. It falls under HTS 2926.30.2000 as it is explicitly named in the tariff description for methadone intermediates with a cyano group directly linked to the carbon chain. The compound consists of a butane backbone with dimethylamino, diphenyl, and cyano substituents, meeting Chapter 29 requirements for separate chemically defined compounds.

Duty Rate — China → United States

41.5%

Rate breakdown

9903.03.0110%Except for products described in headings 9903.03.02–9903.03.11, articles the product of any country, as provided for in subdivision (aa) of U.S. note 2 to this subchapter
9903.88.0325%Except as provided in headings 9903.88.13, 9903.88.18, 9903.88.33, 9903.88.34, 9903.88.35, 9903.88.36, 9903.88.37, 9903.88.38, 9903.88.40, 9903.88.41, 9903.88.43, 9903.88.45, 9903.88.46, 9903.88.48, 9903.88.56, 9903.88.64, 9903.88.66, 9903.88.67, 9903.88.68, or 9903.88.69, articles the product of China, as provided for in U.S. note 20(e) to this subchapter and as provided for in the subheadings enumerated in U.S. note 20(f)

Import Tips

Obtain DEA registration and prior approval for imports due to its status as a controlled substance precursor; ensure all shipments include chemical purity certificates

Provide detailed end-use statements certifying pharmaceutical manufacturing to avoid scrutiny under anti-diversion regulations