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Nebivolol Hydrochloride from Japan

Nebivolol hydrochloride, highly cardioselective with nitric oxide-mediated vasodilation, contains the requisite aromatic oxygen-function amino-compound structure for HTS 2922.50.1400 classification as a cardiovascular drug. Used in hypertension and heart failure management.

Duty Rate — Japan → United States

12.5%

Rate breakdown

9903.05.4912.5%Section 301 (forced labor) — Japan (col1 rate < 12.5 percent): MFN < 12.5% → total duty capped at 12.5%

Import Tips

Stereochemistry critical - specify (R,R,R,R)-enantiomer content >99.5%

Provide particle size distribution data affecting dissolution profiles

Comply with FDA's GDUFA requirements for generic API assessments