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Labetalol Hydrochloride from Japan

Labetalol hydrochloride features dual alpha/beta-blocking activity in an aromatic amino-alcohol-phenol framework with oxygen functions, placing it in HTS 2922.50.1400 for cardiovascular drugs. Primarily indicated for hypertensive emergencies and pregnancy-induced hypertension.

Duty Rate — Japan → United States

12.5%

Rate breakdown

9903.05.4912.5%Section 301 (forced labor) — Japan (col1 rate < 12.5 percent): MFN < 12.5% → total duty capped at 12.5%

Import Tips

Include heavy metals testing (<10 ppm total) per ICH Q3D guidelines

Validate supplier's elemental impurities risk assessment documentation

Use HDPE drums with desiccants for moisture-sensitive hydrochloride salt