Guaiacol USP Grade
Guaiacol is a naturally occurring organic compound classified as an ether-phenol, used primarily as an expectorant in cough syrups and as a chemical intermediate. It falls under HTS 2909.50.4500 as a chemically defined ether-phenol product listed in additional U.S. note 3 to section VI. This monomethoxy phenol derivative is essential in pharmaceutical and flavor applications.
Import Duty Rates by Country of Origin
Alternative Classifications
This product could be classified differently depending on its characteristics or intended use.
If synthetic guaiacol not meeting note 3 specifications
Synthetic ether-phenols excluding those in additional U.S. note 3 fall under the general subheading.
If when imported as fragrance compound for retail perfumery
Mixtures containing guaiacol as fragrance ingredient shift to Chapter 33 for retail preparations.
If formulated as industrial chemical preparation
Blends exceeding 70% guaiacol with additives classify as chemical preparations in Chapter 38.
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Import Tips & Compliance
• Verify USP grade certification and provide detailed chemical analysis (COA) to confirm classification under additional U.S. note 3
• Ensure proper labeling with CAS number (90-05-1) and purity percentage to avoid reclassification as a mixture
• Obtain FDA prior notice for pharmaceutical-grade imports and check REACH compliance for EU-sourced material
Related Products under HTS 2909.50.45.00
4-Methoxyphenol (Mequinol)
4-Methoxyphenol, also known as mequinol, is an ether-phenol used in dermatological treatments for hyperpigmentation and as a polymerization inhibitor. Classified under HTS 2909.50.4500 per additional U.S. note 3 to section VI as a chemically defined ether-phenol derivative. Its phenolic ether structure fits the chapter's specific organic compound criteria.
2-Methoxy-4-methylphenol (Creosol)
Creosol is a methylated ether-phenol compound derived from guaiacol, used as a disinfectant and flavorant in pharmaceuticals. It qualifies for HTS 2909.50.4500 as a product described in additional U.S. note 3 to section VI, meeting the chemically defined ether-phenol classification. The compound's structure features both phenolic hydroxyl and ether functionality.
1-Naphthol-4-methoxy (4-Methoxy-1-naphthol)
4-Methoxy-1-naphthol is a naphthol ether derivative used in dye manufacturing and as a pharmaceutical intermediate. This chemically defined ether-phenol is specifically included under HTS 2909.50.4500 per additional U.S. note 3 to section VI. Its fused ring structure with ether-phenol functionality defines its tariff classification.
2-tert-Butyl-4-methoxyphenol
2-tert-Butyl-4-methoxyphenol serves as an antioxidant in rubber and plastics, featuring ether-phenol functionality. Classified under HTS 2909.50.4500 as a product in additional U.S. note 3 to section VI due to its chemically defined structure. The bulky tert-butyl substitution provides steric hindrance for oxidative stability.
4-Ethoxyphenol
4-Ethoxyphenol is an alkyl ether-phenol used in organic synthesis and as a fragrance intermediate. It meets HTS 2909.50.4500 criteria as a chemically defined ether-phenol specified in additional U.S. note 3 to section VI. The ethoxy substitution distinguishes it from simple phenolic compounds.
3-Methoxyphenol (m-Guaiacol)
m-Guaiacol (3-methoxyphenol) is an isomeric ether-phenol used in pharmaceutical synthesis and as a resin intermediate. Classified under HTS 2909.50.4500 per additional U.S. note 3 to section VI for chemically defined ether-phenols. Its meta-substitution pattern provides unique reactivity profiles.